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CYTOCHROME P-450 CYP2C8
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DeCS
Descriptor
English
:
Cytochrome P-450 CYP2C8
Descriptor
Spanish
:
Citocromo P-450 CYP2C8
Descriptor
Portuguese
:
Citocromo P-450 CYP2C8
Tree Number:
D08.244.453.040.590
D08.811.682.690.708.170.040.590
D12.776.422.220.453.040.590
Definition
English
:
A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of
substrates
including
STEROIDS
,
FATTY ACIDS
, and
XENOBIOTICS
. Examples of pharmaceutical
substrates
for CYP2C8 include; PACLITAXOL; torsemide; and;
AMODIAQUINE
Entry Combination - descr/qualif
English
:
Cytochrome P-450 CYP2C8
/
antagonists & inhibitors
use
Cytochrome P-450 CYP2C8 Inhibitors
History Note
English
:
2015
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55607
Unique Identifier:
D065727
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS